ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2015, Vol. 46 ›› Issue (11): 2085-2096.doi: 10.11843/j.issn.0366-6964.2015.11.023

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Efficacy of Chinese Medicine on Endometritis in Cow:a Systematic Review and Meta-analysis

DONG Shu-wei,ZHANG Shi-dong,WANG Dong-sheng,WANG Hui,MIAO Xiao-lou,YAN Zuo-ting*,YANG Zhi-qiang*   

  1. (Key Laboratory of Veterinary Pharmaceutical Development,Ministry of Agriculture/Key Laboratory of New Animal Drug Project,Gansu Province /Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS,Lanzhou 730050,China)
  • Received:2015-02-12 Online:2015-11-23 Published:2015-11-23

Abstract:

In order to evaluate clinical efficacy of Chinese medicine on endometritis in cows,reports of randomized controlled trials(RCT) were collected from databases of CNKI,Wan Fang,CBM,Pub Med,Web of Science and Science Direct.According to the Cochrane system instruction,Meta-analysis was performed by using RevMan 5.3 software.A total of 24 RCTs,2 782 cases(including 429 cows treated with Chinese medicine,381 cows treated with terramycin,penicillin,streptomycin combined with penicillin and ciprofloxacin) were involved.Meta-analysis results showed that:the total effective rate of Chinese medicine group was better than that of control group[OR=2.40,95%CI(1.74,3.32),P<0.01],but equal to the streptomycin combined with penicillin.The cure rate of Chinese medicine group was better than that of control group[OR=2.40,95%CI(1.74,3.32),P<0.01],but equal to the terramycin.The pregnant rate of Chinese medicine group was better than that of control group.Publication bias analysis showed that the included literature had some certain publication bias.Based on the existed evidence,the efficacy of Chinese medicine on endometritis in Cows is better than that of antibiotics,and the Chinese medicine could improve the pregnant rate of dairy cows.

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